The Fmoc method is a new method for solid phase synthesis of peptides developed by Carpino and Hart based on the Boc method. The fundamental difference between the Fmoc ltd /t-Bu(9-fluorenylmethoxycarbonyl/tert-butoxy) strategy and the Boc/Bzl strategy is the use of alkali-removable Fmoc is a protecting group for α-amino group, the side chain is protected by t-Bu which …
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